TRPM8 antagonist 2 ( —— )

Catalog No. M20423 CAS No. 259674-19-6

TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM used in the research of neuropathic pain syndromes.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

TRPM8 antagonist 2
Note

Research use only not for human use.
Brief Description

TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM used in the research of neuropathic pain syndromes.
Description

TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM used in the research of neuropathic pain syndromes.
Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

TRP/TRPV Channel
Recptor

TRPM8
Research Area

——
Indication

——

Chemical Information

CAS Number

259674-19-6
Formula Weight

398.5
Molecular Formula

C26H26N2O2?
Purity

>98% (HPLC)
Solubility

DMSO:160 mg/mL (401.51 mM)
SMILES

COC(=O)[C@H](Cc1c[nH]c2ccccc12)N(Cc1ccccc1)Cc1ccccc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Alessia B Nunzio I Carmine O et al. Identification of a Potent Tryptophan-based TRPM8 Antagonist With in vivo Analgesic Activity[J]. Journal of Medicinal Chemistry 2018:acs.jmedchem.8b00545-.

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